Change roles with no-hoper (5)
I believe the answer is:
loser
'no-hoper' is the definition.
(I've seen this before)
'change roles' is the wordplay.
'change' indicates anagramming the letters.
'roles' with letters rearranged gives 'LOSER'.
'with' acts as a link.
(Other definitions for loser that I've seen before include "One who is always a failure" , "Winner's opponent" , "Non-achiever" , "Unsuccessful competitor" , "Defeated contestant" .)