Change your mind regarding university originally chosen for Wales (5)
I believe the answer is:
cymru
'for wales' is the definition.
(Cymru is the Welsh word for Wales)
'change your mind regarding university originally chosen' is the wordplay.
'originally chosen' says to take the initial letters.
The first letters of 'change your mind regarding university' is 'CYMRU'.
(Other definitions for cymru that I've seen before include "European country" , "Welsh name for Wales" , "Part of UK" .)