Charge arising from many a nasty bite! (5)
I believe the answer is:
debit
'charge' is the definition.
(I know that charge is a more specific form of the action debit)
'many a nasty bite' is the wordplay.
'many' becomes 'D' (Roman numeral for 500).
'a nasty' indicates anagramming the letters (a nasty or wrong spelling).
'bite' with letters rearranged gives 'ebit'.
'd'+'ebit'='DEBIT'
'arising from' is the link.
(Other definitions for debit that I've seen before include "Accounting entry showing sums owing" , "Charge" , "Opposite of credit" , "Record of a sum owed" , "Deduct from account" .)