Charlie getting on man's nerves in wealthy district (8)

'nerves in wealthy district' is the definition.
I don't know anything about this answer so I cannot tell whether it can be defined by this definition.

'charlie getting on man's' is the wordplay.
I cannot quite see how this works, but
'charlie' could be 'c' (phonetic alphabet: alpha, bravo, charlie etc.) and 'c' is found within the answer.
'man's' could be 'his' and 'his' is found in the answer.
The remaining letters 'wick' is a valid word which might be clued in a way I don't understand.
This may be the basis of clue (or it may be nonsense).

Can you help me to learn more?