Charlie has to put up with a clot (5)
I believe the answer is:
clump
'a clot' is the definition.
(thesaurus)
'charlie has to put up with' is the wordplay.
'charlie' becomes 'c' (phonetic alphabet: alpha, bravo, charlie etc.).
'has' says to put letters next to each other.
'to put up with' becomes 'lump' (I've seen this before).
'c'+'lump'='CLUMP'
(Other definitions for clump that I've seen before include "Small group (of trees)" , "Bunch" , "Compact group of trees, for instance" , "Blow" , "A compact mass" .)