Charlie with last of sticky sweets (5)
I believe the answer is:
candy
'sweets' is the definition.
(I've seen this before)
'charlie with last of sticky' is the wordplay.
'charlie' becomes 'c' (phonetic alphabet: alpha, bravo, charlie etc.).
'with' becomes 'and'.
'last of' indicates one should take the final letters.
The final letter of 'sticky' is 'y'.
'c'+'and'+'y'='CANDY'
(Other definitions for candy that I've seen before include "American confectionary" , "Sugary sweet" , "American sweets" , "Sweet (US)" , "Girl's name (diminutive)" .)