Charming home set up overlooking church (4)
I believe the answer is:
nice
'charming' is the definition.
(thesaurus)
'home set up overlooking church' is the wordplay.
'home' becomes 'in' ('he's home' can mean 'he's in'**).
'set up' says the letters should be written in reverse.
'overlooking' says to put letters next to each other (down clues only).
'church' becomes 'ce' (abbreviation for Church of England).
'in' back-to-front is 'ni'.
'ni'+'ce'='NICE'
(Other definitions for nice that I've seen before include "Pleasant-sounding city in S France" , "good" , "Riviera resort locals call 'La Cote d'Azur'" , "Delightful - French resort" , "Agreeable -- subtle" .)