Cheat Charlie Houseman for one (3)
I believe the answer is:
doc
'houseman for one' is the definition.
(houseman is a kind of doc)
'cheat charlie' is the wordplay.
'cheat' becomes 'do'.
'charlie' becomes 'c' (phonetic alphabet: alpha, bravo, charlie etc.).
'do'+'c'='DOC'
(Other definitions for doc that I've seen before include "Medical practitioner (abbr)" , "GP (colloq.)" , "Disney dwarf" , "GP (informal)" , "bones" .)