Check on home twice (4,2)
I believe the answer is:
rein in
'check' is the definition.
(I've seen this in another clue)
'on home twice' is the wordplay.
'on' becomes 're' ('on' can be mean 'with reference to').
'home' becomes 'in' ('he's home' can mean 'he's in').
'twice' indicates the doubling of some letters.
'in' doubled is 'inin'.
're'+'inin'='REIN IN'
(Other definitions for rein in that I've seen before include "Restrain (someone)" , "Control" , "Person of great power" .)