Check on limits of safety practice (6)
I believe the answer is:
system
'practice' is the definition.
(thesaurus)
'check on limits of safety' is the wordplay.
'check' becomes 'stem' (both can mean to control or stop).
'on' says to put letters next to each other.
'limits of' says to hollow out the word (remove centre letters).
'safety' with its centre removed is 'sy'.
'stem' put after 'sy' is 'SYSTEM'.
(Other definitions for system that I've seen before include "Set of things working together" , "Arrangement of units that function together" , "Organised scheme" , "Organisational method" , "Set of things in a connected whole" .)