Cheese from a can spread with relish (10)
I believe the answer is:
lancashire
'cheese' is the definition.
(I've seen this before)
'a can spread with relish' is the wordplay.
'spread with' indicates anagramming the letters.
'a'+'can'='acan'
'acan' anagrammed with 'relish' can make 'LANCASHIRE'.
'from' acts as a link.
(Other definitions for lancashire that I've seen before include "it includes Leyland" , "Stew from the Northwest" , "Part of country" , "County of NW England" , "Crumbly white cheese" .)