Chemical extracted from chalk -- a lime (6)
I believe the answer is:
alkali
'chemical' is the definition.
(thesaurus)
'extracted from chalk a lime' is the wordplay.
'extracted from' says the answer is hidden in the clue.
'ALKALI' can be found hidden inside 'chalk a lime'.
(Other definitions for alkali that I've seen before include "Eg, lime or caustic soda" , "Soluble compound that turns litmus paper blue" , "Compound turning litmus blue" , "Opposite of acid" , "Antacid" .)