Chest pain could give you a real sting (10)
I believe the answer is:
sternalgia
'chest pain' is the definition.
'could give you a real sting' is the wordplay.
'could give you' is an anagram indicator (the same letters can give another word).
'a'+'real'+'sting'='arealsting'
'arealsting' is an anagram of 'STERNALGIA'.
I've seen this clue in The Independent.
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