Chic male wandering in compound? (8)
I believe the answer is:
chemical
'compound?' is the definition.
(synonyms)
'chic male wandering' is the wordplay.
'wandering' is an anagram indicator.
'chic'+'male'='chicmale'
'chicmale' with letters rearranged gives 'CHEMICAL'.
'in' acts as a link.
(Other definitions for chemical that I've seen before include "Of a substance such as ethanol" , "Artificial compound" , "Laboratory substance" , "Chic male (anag.)" , "Of the interactions of substances" .)