Children came out without daughter (5)
I believe the answer is:
issue
'children' is the definition.
(issue can mean someone's offspring)
I can't explain the rest of the clue.
Can you help me to learn more?
(Other definitions for issue that I've seen before include "Copy of a magazine, for instance" , "Debate topic; flow out" , "Come forth or bring out" , "Point under discussion" , "litter" .)