Children go out (5)
I believe the answer is:
issue
I believe this clue is a double definition.
'children' is the first definition.
(issue can mean someone's offspring)
'go out' is the second definition.
(both can mean emanate from)
(Other definitions for issue that I've seen before include "Put out; result" , "Major topic for debate" , "Important topic for offspring" , "Subject, result, or publication" , "Distribute for sale/use" .)