Children raised in the US sisterhood (5)
I believe the answer is:
issue
'children' is the definition.
(thesaurus)
'raised in the us sisterhood' is the wordplay.
'raised' is a reversal indicator.
'in' indicates the answer is hidden within the clue.
'eussi' can be found hidden inside 'the us sisterhood'.
'eussi' back-to-front is 'ISSUE'.
(Other definitions for issue that I've seen before include "The children to come forth" , "Emanate" , "outlet" , "One's offspring" , "Bring out - children" .)