Children's lives pursue action (5)
I believe the answer is:
issue
'children's' is the definition.
(issue can mean someone's offspring)
'lives pursue action' is the wordplay.
'lives' becomes 'is' ('be' can be a synonym of 'live').
'pursue action' becomes 'sue' (I am not sure about this - if you are sure you should believe this answer much more).
'is'+'sue'='ISSUE'
Can you help me to learn more?
(Other definitions for issue that I've seen before include "Important question" , "Children; important topic" , "Publish, bring out" , "Matter of contention" , "Produce" .)