Church speculation facing endless netherworld (6)
I believe the answer is:
bethel
'church' is the definition.
(I've seen this before)
'speculation facing endless netherworld' is the wordplay.
'speculation' becomes 'bet' (bet is a kind of speculation).
'facing' is a charade indicator (letters next to each other).
'endless' means to remove the last letter.
'netherworld' becomes 'hell' (synonyms).
'hell' with its last letter removed is 'hel'.
'bet'+'hel'='BETHEL'
(Other definitions for bethel that I've seen before include "Methodist or Baptist church; church for seamen" , "Chapel" .)