Chutzpah (5)
I believe the answer is:
nerve
'chutzpah' is the definition.
(I've seen this in another clue)
This is all the clue.
(Other definitions for nerve that I've seen before include "Cool courage" , "Grit" , "Body fibre conveying sensations to brain" , "Boldness" , "Courage to carry on" .)