Circumspect about Italian lady making wine (10)
I believe the answer is:
chardonnay
'wine' is the definition.
(I know that Chardonnay is a type of white wine)
'circumspect about italian lady' is the wordplay.
'circumspect' becomes 'chary' (I've seen this before).
'about' is an insertion indicator.
'italian lady' becomes 'donna' ('lady' in Italian).
'chary' going around 'donna' is 'CHARDONNAY'.
'making' acts as a link.
(Other definitions for chardonnay that I've seen before include "White wine grape" , "Variety of white wine" , "drink" .)