City in Piedmont famed for its sparkling wine (4)
I believe the answer is:
asti
(Other definitions for asti that I've seen before include "White wine named after a town in Piedmont" , "It's a (anag) - wine" , "Italian town producing sparkling wine" , "Capital of a north-west Italian province, known for its sparking wine" , "Piedmont wine city, SE of Turin" .)