Crossword Genius

Clara's upset by rogue (6)

Ross

I believe the answer is:

rascal

'rogue' is the definition.
('rascal' can be a synonym of 'rogue')

'clara's upset' is the wordplay.
'upset' indicates an anagram.
'claras' is an anagram of 'RASCAL'.

'by' acts as a link.

(Other definitions for rascal that I've seen before include "Mischievous or cheeky child" , "Michievous person/child" , "Impudent child" , "mischief-maker" , "Mischievous person or confused lascar" .)

I've seen this clue in The Telegraph.
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