Clean funny comedian with talent forgetting line (13)
I believe the answer is:
decontaminate
'clean' is the definition.
(decontaminating is a kind of cleaning)
'funny comedian with talent forgetting line' is the wordplay.
'funny' indicates an anagram.
'with' is a charade indicator (letters next to each other).
'forgetting' indicates named letters should be taken away.
'line' becomes 'l'.
'comedian'+'talent'='comediantalent'
'comediantalent' with 'l' removed is 'comediantaent'.
'comediantaent' with letters rearranged gives 'DECONTAMINATE'.
(Other definitions for decontaminate that I've seen before include "Remove the bad" , "Remove dangerous substance from (something)" , "Remove pollution from" , "Remove dangerous substances from" , "Purify; make safe" .)