Cleaner burdens grandpa, for one? (6,4)
I believe the answer is:
saddle soap
'cleaner' is the definition.
(I know that Saddle soap is a type of soap)
'burdens grandpa for one?' is the wordplay.
'burdens' becomes 'saddles' ('saddle' can be a synonym of 'burden').
'grandpa for one?' becomes 'oap' (I can't explain this - if you can you should give a lot more credence to this answer).
'saddles'+'oap'='SADDLE SOAP'
Can you help me to learn more?
(Other definitions for saddle soap that I've seen before include "stuff for his work" , "Cleaner" .)