"Cleopatra With the ___" (Reni painting) (3)

I believe the answer is:

asp

(Other definitions for asp that I've seen before include "Cleopatra's supposed nemesis" , "Joe Blake is Australian species" , "Reptile" , "Slithery thing" , "Cleopatra-killing snake" .)

I've seen this clue in The New York Times.

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