Cleo's mad about a politician with 'drive'! (6)
I believe the answer is:
compel
'drive' is the definition.
(I know that drive is a more specific form of the action coerce)
'cleo's mad about a politician' is the wordplay.
'mad' is an anagram indicator.
'about' indicates putting letters inside.
'a politician' becomes 'MP' (Member of Parliament).
'cleo' anagrammed gives 'coel'.
'coel' enclosing 'mp' is 'COMPEL'.
'with' acts as a link.
(Other definitions for compel that I've seen before include "Urge on, force" , "Force, oblige to do something" , "Make someone do something" , "Coerce, force to obey" , "Bring about by force" .)