Climb Andes, shivering, pierced by cold (6)
I believe the answer is:
ascend
'climb' is the definition.
(climb can mean to ascend or go up)
'andes shivering pierced by cold' is the wordplay.
'shivering' is an anagram indicator.
'pierced by' indicates putting letters inside.
'cold' becomes 'c' (eg on taps).
'andes' is an anagram of 'asend'.
'asend' going around 'c' is 'ASCEND'.
(Other definitions for ascend that I've seen before include "Come up" , "Dances (anag.)" , "Move upwards" , "Climb, go up (6)" , "Climb, rise" .)