Clot caused some limb damage (8)
I believe the answer is:
embolism
'clot' is the definition.
(I have seen 'obstructive clot' mean 'embolism' so perhaps 'clot' could also mean 'embolism')
'some limb damage' is the wordplay.
'damage' indicates anagramming the letters (I've seen 'damaged' mean this).
'some'+'limb'='somelimb'
'somelimb' is an anagram of 'EMBOLISM'.
'caused' is the link.
This may not be right. It may belong to another bit of the clue.
Can you help me to learn more?
(Other definitions for embolism that I've seen before include "Obstruction of artery by blood clot" , "Obstruction of a blood vessel as by clot or bubble" , "Blockage by a blood clot" , "Blood vessel blockage" , "Arterial obstruction" .)