Clot, prisoner and American lass taking drug (7)
I believe the answer is:
congeal
'clot' is the definition.
(I've seen this in another clue)
'prisoner and american lass taking drug' is the wordplay.
'prisoner' becomes 'con' (abbreviation for 'convict').
'and' is a charade indicator (letters next to each other).
'american lass' becomes 'gal' (both can mean a girl. I am not sure about the 'american' bit.).
'taking' means one lot of letters goes inside another.
'drug' becomes 'e' (E is another name for ecstasy).
'gal' placed around 'e' is 'geal'.
'con'+'geal'='CONGEAL'
Can you help me to learn more?
(Other definitions for congeal that I've seen before include "Set - go clean (anag)" , "Coagulate" , "cake" , "Cool and solidify" , "Become solid" .)