Cloth can wipe rear end (5)
I believe the answer is:
toile
'cloth' is the definition.
(I've seen this before)
'can wipe rear end' is the wordplay.
'can' becomes 'toilet' (synonyms).
'wipe rear end' means to remove the last letter (wipe the letter at the end of the word off).
'toilet' with its last letter taken off is 'TOILE'.
(Other definitions for toile that I've seen before include "Fabric" , "Worked hard" , "6 [LINEN]" , "cloth" , "dress material" .)