Clothes you and I are having shortened (4)
I believe the answer is:
wear
'clothes' is the definition.
(synonyms)
'you and i are having shortened' is the wordplay.
'you and i' becomes 'we'.
'are having' means one lot of letters go next to another.
'shortened' becomes 'ar' (I can't explain this - if you can you should believe this answer much more).
'we'+'ar'='WEAR'
Can you help me to learn more?
(Other definitions for wear that I've seen before include "Sunderland river" , "Become damaged by use" , "Be clothed in" , "Damage from use" , "Durability" .)