Clues solved with new relations (6)
I believe the answer is:
uncles
'relations' is the definition.
(uncle is a kind of relation)
'clues solved with new' is the wordplay.
'solved with' indicates an anagram (the anagram must be solved).
'new' becomes 'n' (common abbreviation eg NT for New Testament).
'clues' anagrammed with 'n' makes 'UNCLES'.
(Other definitions for uncles that I've seen before include "Helper who looks after another person" , "Relations" , "Older male relatives" , "Kinsmen" .)