Clutched by soprano, second bouquet (4)
I believe the answer is:
nose
'bouquet' is the definition.
(both can mean a smell)
'clutched by soprano second' is the wordplay.
'clutched by' indicates a hidden word.
'NOSE' can be found hidden inside 'soprano second'.
(Other definitions for nose that I've seen before include "See 7" , "See 1" , "Conk (slang)" , "Organ of smell" , "Organ of face" .)