Coagulant affected their neck (9)
I believe the answer is:
thickener
'coagulant' is the definition.
Both the definition and answer are singular nouns.
Perhaps they are linked in a way I don't understand?
'affected their neck' is the wordplay.
'affected' is an anagram indicator.
'their'+'neck'='theirneck'
'theirneck' anagrammed gives 'THICKENER'.
Can you help me to learn more?
(Other definitions for thickener that I've seen before include "Cornflour, for example" , "Such as cornflour in cooking" , "cornflour, perhaps" .)