Cockney's temporary difficulty causes irritation (4)
I believe the answer is:
itch
This clue is a double definition.
'cockney's temporary difficulty' is the first definition.
('hitch' - I've seen this before - said with a cockney accent, dropping the 'H')
'irritation' is the second definition.
(an itch irritates you)
'causes' acts as a link.
(Other definitions for itch that I've seen before include "that's irritating" , "Tickle; urge" , "Irritate" , "Feel tingling sensation in skin" , "A nagging desire" .)