Cold and sick at home, game is outside (10)

'cold' is the definition.
(I know that chilliness is a type of cold)

'sick at home game is outside' is the wordplay.
'sick' becomes 'ill' (synonyms).
'at home' becomes 'in' ('I'm in' can mean 'I'm at home').
'game' becomes 'chess' (board game).
'is outside' means one lot of letters goes inside another (some letters go outside others).
'ill'+'in'='illin'
'illin' placed into 'chess' is 'CHILLINESS'.

'and' acts as a link.