Cold nurse worried rogue (9)
I believe the answer is:
scoundrel
'rogue' is the definition.
(both can mean a dishonourable person)
'cold nurse worried' is the wordplay.
'worried' is an anagram indicator (worry can mean to interfere with or disturb).
'cold'+'nurse'='coldnurse'
'coldnurse' with letters rearranged gives 'SCOUNDREL'.
(Other definitions for scoundrel that I've seen before include "Villain" , "Disreputable type" , "Hound" , "Knave" , "Cad" .)