Colloquially, to create a commotion (5,4)

I believe the answer is:

raise cain

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'create a commotion' is the definition.
(I've seen this before)

I cannot understand how the remainder of the clue works.

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(Other definitions for raise cain that I've seen before include "Make an uproar - lift Abel's brother" , "Make a lot of trouble" , "Make a big commotion (5.4)" , "Create an uproar - elevate murderer" , "Create an unholy row - elevate murderer" .)

I've seen this clue in The Times.

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