Comes to again and feels pain (7)
I believe the answer is:
reaches
'comes to' is the definition.
(I've seen this before)
'again and feels pain' is the wordplay.
'again' becomes 're' (prefix meaning 'again').
'and' is a charade indicator (letters next to each other).
'feels pain' becomes 'aches' (I've seen this in another clue).
're'+'aches'='REACHES'
(Other definitions for reaches that I've seen before include "Succeeds in achieving" , "Hands down" , "River stretches between bends" , "Arrives at" , "Bays" .)