Comfort stop, not the first (4)
I believe the answer is:
ease
'comfort' is the definition.
(easing is a kind of comforting)
'stop not the first' is the wordplay.
'stop' becomes 'cease' (I've seen this before).
'not the first' means to remove the first letter.
'cease' with its initial letter taken away is 'EASE'.
(Other definitions for ease that I've seen before include "Leisure, comfort" , "Effortlessness" , "Facilitate; repose" , "Absence of effort" , "At this, one is relaxed" .)