Comfortable business satisfactorily ends (4)
I believe the answer is:
cosy
'comfortable' is the definition.
(similar in meaning)
'business satisfactorily ends' is the wordplay.
'business' becomes 'co' (short for company).
'ends' means to remove the middle letters.
'satisfactorily' with its centre removed is 'sy'.
'co'+'sy'='COSY'
(Other definitions for cosy that I've seen before include "With a feeling of comfort and warmth" , "Warm, secure" , "Comfortable; teapot cover" , "Intimate" , "Warm and snug" .)