Comic ____ O'Donnell (5)
I believe the answer is:
rosie
'comic o'donnell' is the definition.
(I've seen this in another clue)
This is the entire clue.
(Other definitions for rosie that I've seen before include "Girl's name" , "riveting woman in 40s?" , "literary drinking companion" , "- - Lee (sl.)" , "Char" .)