Commercial and industrial city in northwestern Germany with a major port on the River Weser (6)

I believe the answer is:

bremen

(Other definitions for bremen that I've seen before include "City and state of NW Germany" , "City and state of northwest Germany" , "German port city and state" , "North German city on the Weser" , "Major German port" .)

I've seen this clue in The Independent.

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