Commotion in place of rest left in the morning (6)
I believe the answer is:
bedlam
'commotion' is the definition.
(thesaurus)
'place of rest left in the morning' is the wordplay.
'place of rest' becomes 'bed'.
'left' becomes 'l' (common abbreviation).
'in the morning' becomes 'am'.
'bed'+'l'+'am'='BEDLAM'
'in' acts as a link.
(Other definitions for bedlam that I've seen before include "Noisy confused state" , "Blamed for deafening noise" , "Place of uproar or madness" , "Scene of uproar and confusion" , "State of extreme confusion and disorder" .)