Complaint at use of cane (4)
I believe the answer is:
acne
'complaint' is the definition.
(acne is a kind of health problem)
'use of cane' is the wordplay.
'use of' is an anagram indicator.
'cane' with letters rearranged gives 'ACNE'.
'at' acts as a link.
(Other definitions for acne that I've seen before include "Pimply ailment of adolescnce" , "Spotty skin condition" , "Skin condition prevalent among teenagers" , "Skin rash" , "Cane for the teenager?" .)