Complete agreement on university issue (6)
I believe the answer is:
unison
'complete agreement' is the definition.
(I've seen this before)
'on university issue' is the wordplay.
'on' is a charade indicator (letters next to each other).
'university' becomes 'uni' (I've seen this in other clues).
'issue' becomes 'son' (issue can mean someone's offspring).
'uni' put next to 'son' is 'UNISON'.
(Other definitions for unison that I've seen before include "Complete agreement, harmony" , "Togetherness - TUC member" , "Concord; a trade union" , "Concord; with same pitch" , "A coincidence of musical notes" .)