Complete drink with endless ale (5)
I believe the answer is:
total
'complete' is the definition.
(similar in meaning)
'drink with endless ale' is the wordplay.
'drink' becomes 'tot' (a small alcoholic drink).
'with' says to put letters next to each other.
'endless' means to remove the last letter.
'ale' with its last letter taken away is 'al'.
'tot'+'al'='TOTAL'
(Other definitions for total that I've seen before include "Not qualified" , "Final tally" , "Complete, absolute" , "Ruin" , "wreck" .)