Computer woe (5)
I believe the answer is:
virus
'computer woe' is the definition.
(I've seen this in another clue)
This is all the clue.
(Other definitions for virus that I've seen before include "Organism causing disease, or malicious program in computer" , "Microscopic entity capable of reproducing within cells" , "Corrupting influence" , "Disease carrier or computer bug" , "Cause of computer malfunctions?" .)