Conclude negative response creates hell (7)
I believe the answer is:
inferno
'hell' is the definition.
('inferno' can be a synonym of 'hell')
'conclude negative response' is the wordplay.
'conclude' becomes 'infer' (inferring is a kind of concluding).
'negative response' becomes 'no' (I've seen this in other clues).
'infer'+'no'='INFERNO'
'creates' is the link.
(Other definitions for inferno that I've seen before include "Hellish conflagration" , "Hellish poem" , "Large uncontrolled fire" , "Furious" , "Dante's work" .)